RUVBL1 Polyclonal antibody proteintech 10210-2-AP
$449.00
In stock
SKU
10210-2-AP
ECP54, ECP 54, EC:3.6.4.12, 49 kDa TBP-interacting protein, 49 kDa TBP interacting protein
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse And More (1) | Immunogen: CatNo: Ag0281 Product name: Recombinant human RUVBL1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-214 aa of BC002993 Sequence: MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFD Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, CoIP, CHIP, ELISA | Observed Molecular Weight: 456 aa, 50 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC002993 |
| Conjugate: Unconjugated | Gene Symbol: RUVBL1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 8607 |
| Application: Western Blot (WB) | RRID: AB_2184405 |
| Dilution: WB : 1:1000-1:10000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: RUVBL1 is a member of the AAA (ATPase associated with diverse cellular activities) family of proteins that is associated with several chromatin-remodelling complexes and has important roles in transcriptional regulation, the DNA damage response, telomerase activity, snoRNP assembly, cellular transformation and cancer metastasis[PMID: 21617703]. It consists of 456 amino acids (50 kDa) and interacts with TATA-binding protein (TBP), which is a central component for transcriptional regulation by forming complexes with various transcription regulators. RUVBL1 is a component of a large nuclear protein complex, possibly the RNA polymerase II holoenzyme. RUVBL1 is also highly homologous to RuvB proteins that function as a DNA helicase promote branch migration of the Holliday junction[PMID: 9588198]. This antibody is a rabbit polyclonal antibody to human RUVBL1. |
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