IFIT3 Polyclonal antibody proteintech 15201-1-AP

$449.00
In stock
SKU
15201-1-AP

 

CIG 49, CIG49, GARG 49, IFI 60K, IFI60, IFIT 3, IFIT 4, IFIT3, IFIT4, IRG2, ISG 60, ISG60, RIG G

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human And More (3) Immunogen: CatNo: Ag7349 Product name: Recombinant human IFIT3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 141-490 aa of BC004977 Sequence: EEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN Predict reactive species
 Applications: WB, IHC, IF, CoIP, ChIP, ELISA Observed Molecular Weight: 56 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC004977
Conjugate: Unconjugated Gene Symbol: IFIT3
Tested Applications: Positive WB detected in Gene ID (NCBI): 3437
Application: Western Blot (WB) RRID: AB_2248738
Dilution: WB : 1:2000-1:12000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: IFIT3 (IFN-induced protein with tetratricopeptide repeats 3), also known as IFIT-4, ISG-60 or RIG-G, is a 56 kDa IFN induced protein. IFIT3 has been identified to be associated with strong IFN antiviral activity. Upon RNA virus infection, IFIT3 is significantly induced, ectopic expression or knockdown of IFIT3 could, respectively, enhance or impair IFN regulatory factor 3 (IRF3)-mediated gene expression. IFIT3 thus may serve as an important modulator in innate immunity, revealing a new function of the IFIT family proteins.

 

 

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