E-selectin/CD62E Polyclonal antibody proteintech 20894-1-AP
$449.00
In stock
SKU
20894-1-AP
E-selectin / CD62E, CD62E, E-selectin, CD62 antigen-like family member E, ELAM1
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human | Immunogen: CatNo: Ag14944 Product name: Recombinant human SELE protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 22-371 aa of BC142711 Sequence: WSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALS Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 610 aa, 67 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC142711 |
| Conjugate: Unconjugated | Gene Symbol: CD62E |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 6401 |
| Application: Western Blot (WB) | RRID: AB_10755287 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: E-selectin, also known as ELAM-1 or CD62E, is a member of the selectin family of adhesion molecules that also includes L-selectin and P-selectin. E-selectin is an inducible endothelial cell surface molecule. Its expression on endothelial cells is transcriptionally upregulated by various proinflammatory substances such as IL-1, TNFα and lipopolysaccharide (LPS). Besides, it can be secreted by endothelial cells, and can be detected in a soluble form (sE-selectin) in serum. During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. (PMID: 2827173; 1382417; 8943958) |
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