RANK/TNFRSF11A Polyclonal antibody proteintech 55293-1-AP
$449.00
In stock
SKU
55293-1-AP
TNFRSF11A, TNR11, Receptor activator of NF-KB, Receptor activator of NF KB, RANK
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| Applications: WB, ELISA | Observed Molecular Weight: 80-90 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: TNFRSF11A |
| Conjugate: Unconjugated | Gene Symbol: 8792 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670246 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:1000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Antigen affinity purification |
| Host / Isotype: Polyclonal | Background Information: Tumor necrosis factor receptor superfamily member 11A?(TNFRSF11A, also known as RANK, CD265, and ODFR) is the signaling receptor essential for osteoclast differentiation factor-mediated osteoclastogenesis and is involved in the regulation of interactions between T-cells and dendritic cells (PMID: 9878548). The RANK/RANKL/OPG system is a key regulator in bone resorption, and its dysregulation can lead to pathological bone loss (PMID: 37893470). |
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