Neudesin/NENF Polyclonal antibody proteintech 15760-1-AP
$449.00
In stock
SKU
15760-1-AP
Neudesin / NENF, Neudesin, NENF, Protein GIG47, Neuron-derived neurotrophic factor
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: neuron derived neurotrophic factor |
| Applications: WB, ELISA | Observed Molecular Weight: 19 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NENF |
| Conjugate: Unconjugated | Gene Symbol: 29937 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2150989 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:2000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Antigen affinity purification |
| Host / Isotype: Polyclonal | Background Information: Neudesin neurotrophic factor?(NENF, also known as CIR2, SPUF, and SCIRP10) acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival, which is localized to mitochondria and endoplasmic reticulum by PINK1 and PARK7 (PMID: 31536960). NENF in the adult brain is expected to play roles in the maintenance and protection of neurons in an autocrine/paracrine manner (PMID: 15605373). It greatly increases cAMP levels in neural precursor cells and might activate a Gs-protein-coupled receptor that could activate the MAPK, PKA, and PI-3K signal pathways (PMID: 16547973). |
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