HMGCS1 Polyclonal antibody proteintech 17643-1-AP
$449.00
In stock
SKU
17643-1-AP
EC:2.3.3.10, HMG CoA synthase, HMG-CoA synthase, HMGCS, Hydroxymethylglutaryl-CoA synthase, cytoplasmic
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, mouse, rat | Immunogen: CatNo: Ag11825 Product name: Recombinant human HMGCS1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 171-520 aa of BC083514 Sequence: TGGVGAVALLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIHAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAPDVFAENMKLREDTYHLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARRPTPNDDTLDEGVGLVHSNIATEHIPSPAKKVPRLPATAAEPEAAVISNGEH Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA | Observed Molecular Weight: 520 aa, 57 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC083514 |
| Conjugate: Unconjugated | Gene Symbol: HMGCS1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 3157 |
| Application: Western Blot (WB) | RRID: AB_2248359 |
| Dilution: WB : 1:500-1:1000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: HMGCS1(Hydroxymethylglutaryl-CoA synthase, cytoplasmic) is also named as HMGCS and belongs to the HMG-CoA synthase family. The gene encodes a 520 amino acid protein which catalyzes the condensation of acetyl-CoA and acetoacetyl-CoA into 3-hydroxy-3-methylglutaryl CoA and participates in the mevalonate pathway but its end product is cholesterol(PMID:20346956). The human and hamster enzymes are distinguished by differential inhibition by magnesium ion(PMID:2870496). |
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