XIAP Polyclonal antibody proteintech 10037-1-Ig
$449.00
In stock
SKU
10037-1-Ig
API3, Baculoviral IAP repeat-containing protein 4, E3 ubiquitin-protein ligase XIAP, EC:2.3.2.27, hIAP-3
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, mouse, rat | Immunogen: CatNo: Ag0022 Product name: Recombinant human XIAP protein Source: e coli.-derived, Unknow Tag: N/A Domain: XIAP of BC032729 Sequence: Predict reactive species |
| Applications: WB, IHC, CoIP, ELISA | Observed Molecular Weight: 60 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC032729 |
| Conjugate: Unconjugated | Gene Symbol: XIAP |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 331 |
| Application: Western Blot (WB) | RRID: AB_2215009 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: XIAP, also named as API3, BIRC4 and IAP3, belongs to the IAP family. It has E3 ubiquitin-protein ligase activity. It mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. XIAP is an inhibitor of caspase-3, -7 and -9. It mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B. XIAP is an apoptotic suppressor. It is ubiquitinated and degraded by the proteasome in apoptotic cells. The MW of XIAP is 45-56 kDa. |
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