Cdc20 Polyclonal antibody proteintech 10252-1-AP

$449.00
In stock
SKU
10252-1-AP

 

p55CDC, CDC20A

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human And More (2) Immunogen: CatNo: Ag0295 Product name: Recombinant human CDC20 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-211 aa of BC001088 Sequence: MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSA Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA Observed Molecular Weight: 55 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC001088
Conjugate: Unconjugated Gene Symbol: CDC20
Tested Applications: Positive WB detected in Gene ID (NCBI): 991
Application: Western Blot (WB) RRID: AB_2229016
Dilution: WB : 1:2000-1:14000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Cdc20 (Cell-division cycle protein 20 homologue) is also named as p55CDC and belongs to?the?WD repeat CDC20/Fizzy family. Cdc20 has important functions in chromosome segregation and mitotic exit. Cdc20 is the target of the spindle assembly checkpoint (SAC) and a key cofactor of the anaphase-promoting complex or cyclosome (APC/CCDC20) E3 ubiquitin ligase, thus regulating APC/C ubiquitin activity on specific substrates for their subsequent degradation by the proteasome (PMID:?28202332).?The 55-kDa band corresponded to the size of Cdc20 (PMID:?22566641).

 

 

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