CHMP2A Polyclonal antibody proteintech 10477-1-AP
$449.00
In stock
SKU
10477-1-AP
CHMP2, chromatin modifying protein 2A, Chromatin-modifying protein 2a, hVps2 1, hVps2-1
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (2) | Immunogen: CatNo: Ag0719 Product name: Recombinant human CHMP2A protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-220 aa of BC002502 Sequence: MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLR Predict reactive species |
| Applications: WB, IHC, IF, IP, ELISA | Observed Molecular Weight: 25 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC002502 |
| Conjugate: Unconjugated | Gene Symbol: CHMP2A |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 27243 |
| Application: Western Blot (WB) | RRID: AB_2079470 |
| Dilution: WB : 1:1000-1:5000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: CHMP2A, also known as Vps2-1, belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. CHMP2A is a component of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in the degradation of surface receptor proteins and the formation of endocytic multivesicular bodies (MVBs). It has been shown that CHMP2A can interact with and regulate the function of the AAA-ATPase VPS4B (PMID: 15173323). CHMP2A is also reported to be involved in HIV budding (PMID: 21396898; 23051622). |
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