Alpha Actinin Polyclonal antibody proteintech 11313-2-AP

$449.00
In stock
SKU
11313-2-AP

 

ACTN1, Alpha actinin 1, actin, actinin, alpha 1, ACTN 1

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag1859 Product name: Recombinant human a-Actinin protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 543-892 aa of BC015766 Sequence: EIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQAEYCIARMAPYTGPDSVPGALDYMSFSTALYGESDL Predict reactive species
 Applications: WB, IHC, IF/ICC, IF-P, FC (Intra), ELISA Observed Molecular Weight: 103 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC015766
Conjugate: Unconjugated Gene Symbol: Alpha Actinin
Tested Applications: Positive WB detected in Gene ID (NCBI): 87
Application: Western Blot (WB) RRID: AB_2223815
Dilution: WB : 1:2000-1:10000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Alpha Actinins are highly conserved actin-binding proteins that form antiparallel homodimers with the actin-binding domains on each end of the molecule, allowing crosslinking of actin molecules. There are four alpha actinin isoforms identified: two ubiquitously expressed cytoskeletal isoforms (ACTN1 and ACTN4) and two striated muscle-specific sarcomeric isoforms (ACTN2 and ACTN3). ACTN1 is also alternatively spliced to form smooth muscle or brain specific isoforms. This antibody recognize endogenous ACTN1, while it may cross-react with ACTN2 and ACTN4.

 

 

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