GLUD1 Polyclonal antibody proteintech 14299-1-AP

$449.00
In stock
SKU
14299-1-AP

 

EC:1.4.1.3, GDH, GDH 1, GDH1, GLUD

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (1) Immunogen: CatNo: Ag5694 Product name: Recombinant human GLUD1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 214-558 aa of BC040132 Sequence: FIGPGIDVPAPDMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT Predict reactive species
 Applications: WB, IHC, IF-P, IF-Fro, IP, CoIP, ELISA Observed Molecular Weight: 61 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC040132
Conjugate: Unconjugated Gene Symbol: GLUD1
Tested Applications: Positive WB detected in Gene ID (NCBI): 2746
Application: Western Blot (WB) RRID: AB_2110515
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Human glutamate dehydrogenase (GDH), an enzyme central to the metabolism of glutamate, is known to exist in housekeeping and nerve tissue-specific isoforms encoded by the GLUD1 and GLUD2 genes, respectively. It catalyses the reversible inter-conversion of glutamate to alpha-ketoglutarate and ammonia, thus interconnecting amino acid and carbohydrate metabolism. GLUD1 might contribute to the formation of specific synapses in the hippocampus such as those formed by the projecting neurons of the entorhinal cortex(PMID: 22138648). GLUD1 has a calculated molecular mass of 61 kDa and an apparent molecular mass of 45-55 kDa with the 53aa transit peptide removed.

 

 

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