Cyclin D2 Polyclonal antibody proteintech 10934-1-AP

$449.00
In stock
SKU
10934-1-AP

 

CCND2, G1/S-specific cyclin-D2, G1/S specific cyclin D2, Cyclin D

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse And More (5) Immunogen: CatNo: Ag1377 Product name: Recombinant human CCND2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-289 aa of BC010958 Sequence: MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL Predict reactive species
 Applications: WB, IHC, ELISA Observed Molecular Weight: 32 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC010958
Conjugate: Unconjugated Gene Symbol: Cyclin D2
Tested Applications: Positive WB detected in Gene ID (NCBI): 894
Application: Western Blot (WB) RRID: AB_2275319
Dilution: WB : 1:500-1:2000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: CCND2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. CCND2 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of CCND2 was observed in ovarian and testicular tumors.

 

 

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