SPHK1 Polyclonal antibody proteintech 10670-1-AP

$449.00
In stock
SKU
10670-1-AP

 

Acetyltransferase SPHK1, EC:2.3.1.-, EC:2.7.1.91, SK1, Sphingosine kinase 1

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human And More (2) Immunogen: CatNo: Ag1051 Product name: Recombinant human SPHK1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 85-384 aa of BC008040 Sequence: HEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLLLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSGCVEPPPSWKPQQMPPPEEPL Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA, Cell treatment Observed Molecular Weight: 43 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC008040
Conjugate: Unconjugated Gene Symbol: SPHK1
Tested Applications: Positive WB detected in Gene ID (NCBI): 8877
Application: Western Blot (WB) RRID: AB_2195809
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: SPHK(Sphingosine kinase 1) is also named as SPHK, SPK.It catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions and is precariously perched at the balance point between progrowth and pro-death signalling in the cell.Endogenous SPHK1 purified from placenta has identical enzymatic characteristics, suggesting posttranslational modification does not effect functional properties(PMID:10947957).It has 2 isoforms produced by alternative splicing and can form the oligomeric structure(PMID:22335554).

 

 

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