CD14 Polyclonal antibody proteintech 17000-1-AP

$449.00
In stock
SKU
17000-1-AP

 

CD14 molecule, Monocyte differentiation antigen CD14, membrane-bound form, Monocyte differentiation antigen CD14, urinary form, Myeloid cell-specific leucine-rich glycoprotein

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Pig And More (2) Immunogen: CatNo: Ag10693 Product name: Recombinant human CD14 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-375 aa of BC010507 Sequence: MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIHAGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKELTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQAHSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA Predict reactive species
 Applications: WB, IHC, IF/ICC, IF-P, ELISA Observed Molecular Weight: 375 aa, 40 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC010507
Conjugate: Unconjugated Gene Symbol: CD14
Tested Applications: Positive IHC detected in Gene ID (NCBI): 929
Application: Immunohistochemistry (IHC) RRID: ENSG00000170458
Dilution: IHC : 1:1000-1:4000 Conjugate: AB_2074048
Tested Reactivity: Human, Mouse, Pig Form: Unconjugated
Host / Isotype: Rabbit / IgG Background Information: CD14 is a 50-55 kDa glycosylphosphatidylinositol-anchored glycoprotein preferentially expressed on monocytes and macrophages, and at lower levels on granulocytes (PMID: 3385210; 2462937; 7685797). CD14 can also exist as a soluble protein. CD14 acts as a co-receptor for bacterial liposaccharides (LPS) (PMID: 1698311). It plays a major role in the inflammatory response of monocytes to LPS.

 

 

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