WWTR1/TAZ Polyclonal antibody proteintech 23306-1-AP
$449.00
In stock
SKU
23306-1-AP
TAZ, WWTR1, Transcriptional coactivator with PDZ-binding motif, WW domain-containing transcription regulator protein 1
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Rat And More (1) | Immunogen: CatNo: Ag19659 Product name: Recombinant human WWTR1,TAZ protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-400 aa of BC014052 Sequence: MNPASAPPPLPPPGQQVIHVTQDLDTDLEALFNSVMNPKPSSWRKKILPESFFKEPDSGSHSRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHPAVSSTPVPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQQQQQQKLRLQRIQMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDMRSITNNSSDPFLNGGPYHSREQSTDSGLGLGCYSVPTTPEDFLSNVDEMDTGENAGQTPMNINPQQTRFPDFLDCLPGTNVDLGTLESEDLIPLFNDVESALNKSEPFLTWL Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, CoIP, ChIP, ELISA | Observed Molecular Weight: 44 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC014052 |
| Conjugate: Unconjugated | Gene Symbol: WWTR1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 25937 |
| Application: Western Blot (WB) | RRID: AB_2721185 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: TAZ, also referred as WWTR1, is a transcriptional co-activator with a PDZ-binding motif that is regulated by its interaction with 14-3-3 protein. TAZ is expressed in many primary tumors, such as breast cancer, thyroid carcinoma, colorectal cancer, and glioma (PMID: 22003437, PMID: 27764783). TAZ has been reported to be one of the nuclear effectors of Hippo-related pathways that regulate organ size control, cancer stem cell (CSC) properties, and epithelial-mesenchymal transition (EMT).?TAZ has been defined for its role in the nucleus, where it functions directly as a transcriptional regulator by interacting with several nuclear factors as Runx2/Cbfa1, NHERF-2, TEF-1, TBX5, PAX3, PAX8 and TTF-1. |
Reviews
Write Your Own Review