SMCR7L/MID51 Polyclonal antibody proteintech 20164-1-AP
$449.00
In stock
SKU
20164-1-AP
HSU79252, MID51, MIEF1, SMCR7L, SMCR7L/MID51
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, mouse, rat and More (2) | Immunogen: CatNo: Ag13775 Product name: Recombinant human SMCR7L protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-359 aa of BC002587 Sequence: FDTDTFCPPRPKPVARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEVQYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT Predict reactive species |
| Applications: WB, IHC, IF, IP, ELISA | Observed Molecular Weight: 463 aa, 51 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC002587 |
| Conjugate: Unconjugated | Gene Symbol: SMCR7L |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 54471 |
| Application: Western Blot (WB) | RRID: AB_10639522 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: human, mouse, rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa (also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates. |
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