SOCS3 Polyclonal antibody proteintech 14025-1-AP
$449.00
In stock
SKU
14025-1-AP
ATOD4, CIS3, CIS-3, Cytokine-inducible SH2 protein 3, SOCS-3
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (4) | Immunogen: CatNo: Ag5170 Product name: Recombinant human SOCS3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-225 aa of BC060858 Sequence: MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPSAQPLPGSPPRRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL Predict reactive species |
| Applications: WB, IHC, IF, IP, CoIP, ELISA | Observed Molecular Weight: 25 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC060858 |
| Conjugate: Unconjugated | Gene Symbol: SOCS3 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 9021 |
| Application: Western Blot (WB) | RRID: AB_10597854 |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: The suppressor of cytokine signaling (SOCS) family proteins are negative feedback system that inhibits cytokine signal transduction. One of the SOCS family, SOCS3, also named CIS3 and SSI3, is involved in inhibition of JAK/STAT pathway which regulates IL-6 signaling in vivo. SOCS3 can be rapidly trigger by a number of factors including interleukins, IFN-gamma and TNF-alpha. Pathology such as inflammatory response, wound repair and obesity and so on have been linked to SOCS3. Observed MW of SOCS3 is from 22-30 kDa(PMID: 24827536,PMID: 26260587, PMID: 26797799), consistent with the result of Catalog#14025-1-AP. |
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