ULK1 Polyclonal antibody proteintech 20986-1-AP

$449.00
In stock
SKU
20986-1-AP

 

ATG1, Autophagy-related protein 1 homolog, EC:2.7.11.1, hATG1, KIAA0722

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (2) Immunogen: Peptide Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, ELISA Observed Molecular Weight: 113 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: NM_003565
Conjugate: Unconjugated Gene Symbol: ULK1
Tested Applications: Positive WB detected in Gene ID (NCBI): 8408
Application: Western Blot (WB) RRID: AB_2878783
Dilution: WB : 1:500-1:2000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase (FAK) family interacting protein of 200?kDa?(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).

 

 

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