ALPL Polyclonal antibody proteintech 11187-1-AP

$449.00
In stock
SKU
11187-1-AP

 

Alkaline phosphatase, AKP2, Alkaline phosphatase liver/bone/kidney isozyme, Alkaline phosphatase tissue nonspecific isozyme, Alkaline phosphatase, tissue-nonspecific isozyme

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: human Immunogen: CatNo: Ag1664 Product name: Recombinant human ALPL protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 23-330 aa of BC021289 Sequence: EKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLL Predict reactive species
 Applications: WB, IHC, IF/ICC, FC (Intra), chIP, ELISA Observed Molecular Weight: 57 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC021289
Conjugate: Unconjugated Gene Symbol: ALPL
Tested Applications: Positive WB detected in Gene ID (NCBI): 249
Application: Western Blot (WB) RRID: AB_2305523
Dilution: WB : 1:500-1:2000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. ALPL(Alkaline phosphatase, tissue-nonspecific isozyme) is also named as AP-TNAP, TNSALP and belongs to the alkaline phosphatase family. It can exsit as a homodimer with the molecular weight of 140 kDa(PMID:18724009). ALPL was synthesized as a 66-kDa endo-b-N-acetylglucos-aminidase H (Endo H)-sensitive form, and processed to an 80-kDa mature form, which is anchored to the plasma membrane via glycosylphosphatidylinositol (GPI)(PMID:10839996).This antibody can bind the four mentioned alkaline phosphatases.

 

 

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