Anti-Human Nectin-2/CD112 Rabbit Recombinant Antibody proteintech 98283-1-RR
$74.00
In stock
SKU
98283-1-RR
Nectin-2, Nectin 2, HVEB, Herpesvirus entry mediator B, Herpes virus entry mediator B
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| Applications: FC | Observed Molecular Weight: NM_001042724.2 |
| Formulation: PBS, Azide | GenBank Accession Number: 5819 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purfication |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Q92692-2 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: Nectin 2, also named as PVRL2, CD112, HVEB, PRR2 and PVRR2, is an adhesion molecule widely expressed in cell lines of different lineages, including hematopoietic, neuronal, endothelial and epithelial cells. CD112 belongs to a new family of immunoglobulin-like molecules that includes four members (CD111, CD112, PRR3 and CD155) sharing an ectodomain made of three Ig domains, of V and C types. CD112 is expressed in the myelo-monocytic and megakaryocytic hematopoietic lineages and the function in hematopoiesis is currently unknown. CD112 is an intercellular homophilic adhesion. CD112 localizes specifically at adherents junctions via its cytoplasmic interaction with the scaffold F-actin binding protein afadin. Disruption of the murine CD112 gene leads to infertility of male mice with morphologically aberrant spermatozoa. CD112 mediates entry of some alphaherpesvirus mutants (also named HveB) via its V domain. CD112 is involved in cell to cell spreading of viruses. |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
