Anti-Human MICA/MICB Rabbit Recombinant Antibody proteintech 98110-1-RR
$71.00
In stock
SKU
98110-1-RR
MICB, MICA, PERB11.1, MIC A, 240735D5
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: MHC class I polypeptide-related sequence A |
| Applications: FC | Observed Molecular Weight: / |
| Formulation: PBS, Azide | GenBank Accession Number: 4276 |
| Conjugate: Unconjugated | Gene Symbol: AB_3672257 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: Q29983 |
| Host / Isotype: Recombinant | Background Information: Human MHC class I chain-related genes located within the HLA class I region of chromosome 6 encode MHC class I chain-related A and B (MICA and MICB) (PMID: 11429322). MICA and MICB are stress-inducible surface molecules that are not associated with β2-microglobulin and do not present peptides (PMID: 9497295). They are expressed in intestinal epithelium and many epithelial tumors (PMID: 10359807). MICA and MICB are ligands for NKG2D which is an activating receptor that is expressed on most natural killer (NK) cells, CD8 αβ T cells, and γδ T cells (PMID: 10426993; 11491531). This antibody recognizes both MICA and MICB. |
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