Anti-Human LRP1 (5A6) Mouse IgG2a Recombinant Antibody proteintech 65594-1-MR
$149.00
In stock
SKU
65594-1-MR
5A6, A2MR, Alpha 2 macroglobulin receptor, Alpha-2-macroglobulin receptor, APOER
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) |
| Applications: FC | Observed Molecular Weight: BC045107 |
| Formulation: PBS, Azide | GenBank Accession Number: 4035 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purification |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: Q07954 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: LRP1 (Prolow-density lipoprotein receptor-related protein 1), also known as A2MR, APOER and CD91, is a type I transmembrane protein that belongs to the LDLR family. LRP1 is synthesized as a transmembrane glycosylated precursor of 600 kDa, and is subsequently cleaved to generate a large 515-kDa N-terminal extracellular subunit and an 85-kDa C-terminal transmembrane subunit, which are noncovalently associated with one another (PMID: 2112085; 8546712). LRP1 is a multifunctional receptor involved in the clearance of a large number of diverse ligands and modulating various cellular processes. LRP1 is implicated in conditions such as atherosclerosis, cancer and neurodegenerative diseases (PMID: 28381441). |
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