Anti-Human LIFR Rabbit Recombinant Antibody proteintech 98432-2-RR
$190.00
In stock
SKU
98432-2-RR
CD118, LIF R, LIF receptor, LIF-R, SJS2
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: leukemia inhibitory factor receptor alpha |
| Applications: FC | Observed Molecular Weight: NM_001127671.1 |
| Formulation: PBS, Azide | GenBank Accession Number: 3977 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purification |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: P42702-1 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: LIFR, also known as CD118, is a subunit of a receptor for leukemia inhibitory factor (LIF). LIF is a pleiotropic cytokine of the interleukin-6 family that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR is the low-affinity binding chain that, together with the high-affinity converter subunit gp130, forms a high-affinity receptor complex that mediates the action of LIF. The high-affinity complex also binds a related cytokine, oncostatin M (PMID: 8999038). LIFR has also been identified as a breast cancer metastasis suppressor that functions through the HIPPO-YAP pathway (PMID: 23001183). |
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