Anti-Human IL-6 Rabbit Recombinant Antibody proteintech 98087-1-RR
$60.00
In stock
SKU
98087-1-RR
IL6, 240670D12, B-cell stimulatory factor 2, IFN-beta-2, IL 6
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: interleukin 6 (interferon, beta 2) |
| Applications: FC (Intra) | Observed Molecular Weight: BC015511 |
| Formulation: PBS, Azide | GenBank Accession Number: 3569 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000136244 |
| Tested Applications: Positive FC (Intra) detected in | Gene ID (NCBI): AB_3672234 |
| Application: Flow Cytometry (FC) (INTRA) | RRID: Unconjugated |
| Dilution: FC (INTRA) : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity. |
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