Anti-Human HER2/ErbB2 Rabbit Recombinant Antibody proteintech 98304-3-RR

$124.00
In stock
SKU
98304-3-RR

 

ERBB2, CD340, HER 2, HER 2/neu, HER2

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human Immunogen: v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
 Applications: FC Observed Molecular Weight: BC156755
Formulation: PBS, Azide GenBank Accession Number: 2064
Conjugate: Unconjugated Gene Symbol: Unconjugated
Tested Applications: Positive FC detected in Gene ID (NCBI): Liquid
Application: Flow Cytometry (FC) RRID: Protein A purification
Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension Conjugate: P04626
Tested Reactivity: Human Form: PBS with 0.09% sodium azide, pH 7.3.
Host / Isotype: Recombinant Background Information: HER2, also known as ErbB2, Neu, and CD340, is a 185-kDa transmembrane glycoprotein member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. It has no ligand-binding domain and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.

 

 

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