CNOT1 Polyclonal antibody proteintech 14276-1-AP

$449.00
In stock
SKU
14276-1-AP

 

AD 005, AD-005, CCR4-associated factor 1, CCR4-NOT transcription complex subunit 1, CDC39

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (1) Immunogen: CatNo: Ag5623 Product name: Recombinant human CNOT1 protein Source: e coli.-derived, T-HIS Tag: 6*His Domain: 1-354 aa of BC040523 Sequence: MNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGDGKSSGKDFHQTQFLIQECALLITKPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGFQDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVGYGFCASIEECRNIIVQFGVREVTAAQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLNF Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, chIP, RIP, ELISA Observed Molecular Weight: 267 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC040523
Conjugate: Unconjugated Gene Symbol: CNOT1
Tested Applications: Positive WB detected in Gene ID (NCBI): 23019
Application: Western Blot (WB) RRID: AB_10888627
Dilution: WB : 1:500-1:1000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: CNOT1 is a component of CCR4-NOT protein complex, which is a regulator of RNA polymerase II transcription, acts as a transcription repressor. CCR4-NOT complex could participate in transcription as well as mRNA degradation. It's highly expressed in brain, heart, thymus, but weak in skeletal muscle and colon. CNOT1 undergoes alternative splicing to produce four isoforms.This is a rabbit polyclonal antibody raised against part chain of C-terminal CNOT1 of human origin. CNOT1 exsits as many isoforms and molecular weight of isoforms are 267, 241 and 173 kDa.

 

 

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