Anti-Human E-selectin/CD62E Rabbit Recombinant Antibody proteintech 98189-1-RR
$71.00
In stock
SKU
98189-1-RR
CD62E, E-selectin, ELAM 1, ELAM, E selectin
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: selectin E |
| Applications: FC | Observed Molecular Weight: BC142711 |
| Formulation: PBS, Azide | GenBank Accession Number: 6401 |
| Conjugate: Unconjugated | Gene Symbol: AB_3672328 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: P16581 |
| Host / Isotype: Recombinant | Background Information: E-selectin, also known as CD62E or ELAM-1, is a member of the selectin family of adhesion molecules that also includes L-selectin and P-selectin. E-selectin is an inducible endothelial cell surface molecule. Its expression on endothelial cells is transcriptionally upregulated by various proinflammatory substances such as IL-1, TNFα and lipopolysaccharide (LPS). Besides, it can be secreted by endothelial cells, and can be detected in a soluble form (sE-selectin) in serum. During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. (PMID: 2827173; 1382417; 8943958) |
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