Anti-Human CXCR4/CD184 Rabbit Recombinant Antibody proteintech 98175-1-RR
$115.00
In stock
SKU
98175-1-RR
CXCR4, 241735F8, CD184, C-X-C chemokine receptor type 4, CXC R4
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: chemokine (C-X-C motif) receptor 4 |
| Applications: FC | Observed Molecular Weight: BC020968 |
| Formulation: PBS, Azide | GenBank Accession Number: 7852 |
| Conjugate: Unconjugated | Gene Symbol: AB_3672318 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: P61073 |
| Host / Isotype: Recombinant | Background Information: C-X-C chemokine receptor type 4 (CXCR4, also known as CD184) is a widely expressed G protein-coupled seven-transmembrane receptor. CXCL12/SDF-1 is the biological ligand for CXCR4. The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription (PMID: 20484021). CXCR4 also functions as a coreceptor for HIV-1 entry (PMID: 9427609). |
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