Anti-Human CD86 (BU63) Mouse IgG2a Recombinant Antibody proteintech 65592-1-MR
$105.00
In stock
SKU
65592-1-MR
CD28LG2, BU63, B70, B7 2, Activation B7-2 antigen
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: CD86 molecule |
| Applications: FC | Observed Molecular Weight: BC040261 |
| Formulation: PBS, Azide | GenBank Accession Number: 942 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000114013 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3670341 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. |
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