Anti-Human CD83 (HB15e) Mouse IgG2a Recombinant Antibody proteintech 65581-1-MR
$111.00
In stock
SKU
65581-1-MR
B cell activation protein, B-cell activation protein, BL11, CD83 antigen, CD83 molecule
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human, non-human primates | Immunogen: CD83 molecule |
| Applications: IF/ICC, FC | Observed Molecular Weight: BC030830 |
| Formulation: PBS, Azide | GenBank Accession Number: 9308 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000112149 |
| Tested Applications: Positive IF/ICC detected in | Gene ID (NCBI): AB_3670333 |
| Application: Immunofluorescence (IF)/ICC | RRID: Unconjugated |
| Dilution: IF/ICC : 1:50-1:500 | Conjugate: Liquid |
| Tested Reactivity: Human, Non-Human Primates | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928). |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
