Anti-Human CD74 Rabbit Recombinant Antibody proteintech 98478-2-RR
$71.00
In stock
SKU
98478-2-RR
Class-II-associated invariant chain peptide, DHLAG, HLADG, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD74 molecule, major histocompatibility complex, class II invariant chain |
| Applications: FC | Observed Molecular Weight: NM_001025159.3 |
| Formulation: PBS, Azide | GenBank Accession Number: 972 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purification |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: P04233-2 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: CD74, also known as MHC class II invariant chain Ii or HLA-DR-associated invariant chain, is a non-polymorphic type II transmembrane glycoprotein. CD74 is mainly distributed in B cells, monocytes, Langerhans cells, dendritic cells and thymic epithelial cells, and is also expressed in epithelial cells. CD74 plays a key role in MHC class II antigen processing and also serves as a cell surface receptor for the macrophage cytokine MIF. CD74 plays an important role in cardiovascular diseases such as atherosclerosis, ischemic heart disease, and myocardial hypertrophy.(PMID: 15475450; PMID: 27752708; PMID: 38992165; PMID: 36712241). |
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