Anti-Human CD6 Rabbit Recombinant Antibody proteintech 98223-1-RR
$105.00
In stock
SKU
98223-1-RR
241965C9, CD6 molecule, Soluble CD6, T12, T-cell differentiation antigen CD6
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD6 molecule |
| Applications: FC | Observed Molecular Weight: CD6 |
| Formulation: PBS, Azide | GenBank Accession Number: Unconjugated |
| Conjugate: Unconjugated | Gene Symbol: Liquid |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Protein A purfication |
| Application: Flow Cytometry (FC) | RRID: P30203 |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: PBS with 0.09% sodium azide, pH 7.3. |
| Tested Reactivity: Human | Form: Store at 2 - 8°C. Stable for one year after shipment. |
| Host / Isotype: Recombinant | Background Information: CD6 is a type I transmembrane glycoprotein that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harboring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands. |
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