YME1L1 Polyclonal antibody proteintech 11510-1-AP

$449.00
In stock
SKU
11510-1-AP

 

Meg 4, FTSH1, FTSH, EC:3.4.24.-, ATP-dependent zinc metalloprotease YME1L1

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (1) Immunogen: CatNo: Ag2069 Product name: Recombinant human YME1L1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 348-716 aa of BC023507 Sequence: GSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA Observed Molecular Weight: 716 aa, 80 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC023507
Conjugate: Unconjugated Gene Symbol: YME1L1
Tested Applications: Positive WB detected in Gene ID (NCBI): 10730
Application: Western Blot (WB) RRID: AB_2217459
Dilution: WB : 1:500-1:2000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: YME1L1(ATP-dependent zinc metalloprotease) is also named as FTSH1, YME1L,Meg-4,PAMP. YME1L1 plays a phylogenetically conserved role in mitochondrial protein metabolism.It also ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. YME1L1 can prevent mitochondrial DNA inserting into nuclear. It has 3 isoforms produced by alternative splicing with the molecular weight of 86 kDa, 80 kDa and 76 kDa. This protein can migrate with a molecular weight of about 55-63 kDa, which is the size of the mature YME1L1 protein(PMID:22252130; 22354088).

 

 

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