Anti-Human CD49b (AK7) Mouse IgG2a Recombinant Antibody proteintech 65583-1-MR
$78.00
In stock
SKU
65583-1-MR
ITGA2, AK7, BR, Collagen receptor, GPIa
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| Applications: FC | Observed Molecular Weight: NM_002203 |
| Formulation: PBS, Azide | GenBank Accession Number: 3673 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purification |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: P17301 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: CD49b, also known as alpha2 integrin, is a type I transmembrane glycoprotein which forms an adhesion molecule VLA-2 with beta1 integrin. CD49b is a receptor for many (extracellular) matrix and non-matrix molecules (PMID: 23847623). CD49b is expressed on numerous cell types including platelets, activated T cells, B cells, and monocytes. CD49b activation skews NK cell effector function to a phenotype that exhibits elevated IFN-γ production with a concomitant inhibition of motility and cytolytic function (PMID: 32971468, 32762681). The Anti-Human CD49b antibody, clone AK7, is derived from Human platelets. |
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