Anti-Human CD314/NKG2D (1D11) Mouse IgG2a Recombinant Antibody proteintech 65643-1-MR
$71.00
In stock
SKU
65643-1-MR
KLRK1, CD314, 1D11, KLR, Killer cell lectin-like receptor subfamily K member 1
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: killer cell lectin-like receptor subfamily K, member 1 |
| Applications: FC | Observed Molecular Weight: BC039836 |
| Formulation: PBS, Azide | GenBank Accession Number: 22914 |
| Conjugate: Unconjugated | Gene Symbol: AB_3670372 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Protein A purification |
| Tested Reactivity: Human | Form: P26718 |
| Host / Isotype: Recombinant | Background Information: CD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In humans, it is expressed on NK cells, gamma delta T cells, and CD8+ alpha beta T cells (PMID: 10426993). Various families of cell surface ligands have been identified, including the MICA/MICB and ULBP proteins (PMID: 12150888). CD314 is involved in both innate and adaptive immunities, and the NKG2D/NKG2DL pathway involves multiple effector cell types for controlling tumor progression (PMID: 31720075). |
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