Anti-Human CD28 Rabbit Recombinant Antibody proteintech 98032-1-RR
$59.00
In stock
SKU
98032-1-RR
240354D2, CD28 molecule, T-cell-specific surface glycoprotein CD28, Tp44
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, monkey, non-human primates | Immunogen: CD28 molecule |
| Applications: FC | Observed Molecular Weight: BC093698 |
| Formulation: PBS, Azide | GenBank Accession Number: 940 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000178562 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3672177 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human, Monkey, Non-Human Primates | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: CD28 (T-cell-specific surface glycoprotein CD28), also known as T44 and Tp44, is a 44 kD disulfide-linked homodimeric type I glycoprotein (PMID: 2162180). It is a member of the immunoglobulin superfamily and is expressed on most T lineage cells, NK cell subsets, and plasma cells (PMID: 2162180, 8386518). CD28 may affect in vivo immune responses by functioning both as a cell adhesion molecule linking B and T lymphocytes and as the surface component of a novel signal transduction pathway (PMID: 2162180, 3021470). CD28 binds both CD80 and CD86 with a highly conserved motif MYPPY in the CDR3-like loop (PMID: 15696168, 7964482). CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death (PMID: 1348520). |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
