Anti-Human CD27 Rabbit Recombinant Antibody proteintech 98346-3-RR
$68.00
In stock
SKU
98346-3-RR
T cell activation antigen CD27, S152, CD27L receptor, CD27 molecule, CD27 antigen
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD27 molecule |
| Applications: FC | Observed Molecular Weight: BC012160 |
| Formulation: PBS, Azide | GenBank Accession Number: 939 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000139193 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Protein A purification |
| Tested Reactivity: Human | Form: P26842 |
| Host / Isotype: Recombinant | Background Information: CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (CD27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1. |
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