Anti-Human CD268/BAFF-R Rabbit Recombinant Antibody proteintech 98254-1-RR
$124.00
In stock
SKU
98254-1-RR
TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: tumor necrosis factor receptor superfamily, member 13C |
| Applications: FC | Observed Molecular Weight: BC105123 |
| Formulation: PBS, Azide | GenBank Accession Number: 115650 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purfication |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Q96RJ3 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453). |
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