Anti-Human CD226 (11A8) Mouse IgG2a Recombinant Antibody proteintech 65573-1-MR
$74.00
In stock
SKU
65573-1-MR
DNAM-1, DNAM1, DNAM 1, CD226 molecule, CD226 antigen
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: CD226 molecule |
| Applications: FC | Observed Molecular Weight: BC074787 |
| Formulation: PBS, Azide | GenBank Accession Number: 10666 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000150637 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3670327 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383). |
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