Anti-Human CD21 (BU32) Mouse IgG2a Recombinant Antibody proteintech 65591-1-MR
$67.00
In stock
SKU
65591-1-MR
C3DR, CD21, Complement C3d receptor, Complement receptor type 2, CR2, EBV receptor, Epstein Barr virus receptor, SLEB9
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: Human | Immunogen: complement component (3d/Epstein Barr virus) receptor 2 |
| Applications: FC | Observed Molecular Weight: BC136394 |
| Formulation: PBS, Azide | GenBank Accession Number: 1380 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000117322 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3670340 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CD21, also known as complement receptor type 2 (CR2), complement C3d receptor, and Epstein-Barr virus receptor, is a transmembrane protein that contains a small cytoplasmic domain, a transmembrane region and an extracellular domain consisting of 15 tandem short consensus repeat sequences (PMID: 6230668; 2551147). It is expressed on B cells, follicular dendritic cells, thymocytes and a subset of peripheral T cells (PMID: 26119182). CD21 binds complement fragments C3d, C3dg and iC3b and acts as a receptor for the Epstein-Barr virus (PMID: 7753047). On B cells, together with CD19 and CD81, CD21 forms a complex that functions as a co-receptor to the BCR (PMID: 7542009). It is involved in B cells activation and functions. |
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