Anti-Human CD16 (3G8) Mouse IgG2a Recombinant Antibody proteintech 65612-1-MR
$66.00
In stock
SKU
65612-1-MR
3G8, CD16A, CD16a antigen, CD16-II, Fc gamma RIII
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human, monkey, non-human primates | Immunogen: Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
| Applications: FC | Observed Molecular Weight: BC017865 |
| Formulation: PBS, Azide | GenBank Accession Number: 2214 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000203747 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3670359 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: Liquid |
| Tested Reactivity: Human, Monkey, Non-Human Primates | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B. Clone 3G8 recognizes both the CD16a and CD16b (PMID: 7592758). |