Anti-Human CD134/OX40 Rabbit Recombinant Antibody proteintech 98181-1-RR
$71.00
In stock
SKU
98181-1-RR
TNFRSF4, OX40L receptor, OX40, CD134, ACT35 antigen
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: tumor necrosis factor receptor superfamily, member 4 |
| Applications: FC | Observed Molecular Weight: NM_003327 |
| Formulation: PBS, Azide | GenBank Accession Number: 7293 |
| Conjugate: Unconjugated | Gene Symbol: AB_3672322 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: P43489 |
| Host / Isotype: Recombinant | Background Information: CD134, also known as OX40 and TNFRSF4, is a member of the TNFR-superfamily of receptors (PMID: 2828930; 9766631). It is a type I transmembrane protein predominantly expressed on activated T cells which include CD4 and CD8 T cells, Th2, Th1, and Th17 cells, as well as regulatory T cells (Tregs) (PMID: 20307208). CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule (PMID: 26215166). CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmune diseases, cancer and infectious disease (PMID: 26215166; 19426222). |
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