Anti-Human CD11c (3.9) Mouse IgG2a Recombinant Antibody proteintech 65568-1-MR
$63.00
In stock
SKU
65568-1-MR
3.9, CD11 antigen-like family member C, Integrin alpha X, Integrin alpha-X, ITGAX
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: integrin, alpha X (complement component 3 receptor 4 subunit) |
| Applications: FC | Observed Molecular Weight: BC038237 |
| Formulation: PBS, Azide | GenBank Accession Number: 3687 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000140678 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3670322 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.5 ug per 10^6 cells in a 100 ?l suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533). |
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