Anti-Human CD107b / LAMP2 (H4B4) Mouse IgG2a Recombinant Antibody proteintech 65566-1-MR
$68.00
In stock
SKU
65566-1-MR
CD107b, LAMP2, CD107 antigen-like family member B, H4B4, LAMP 2
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: lysosomal-associated membrane protein 2 |
| Applications: IF/ICC, FC (Intra) | Observed Molecular Weight: BC002965 |
| Formulation: PBS, Azide | GenBank Accession Number: 3920 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000005893 |
| Tested Applications: Positive IF/ICC detected in | Gene ID (NCBI): AB_3670320 |
| Application: Immunofluorescence (IF)/ICC | RRID: Unconjugated |
| Dilution: IF/ICC : 1:250-1:1000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: LAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells (PMID: 12221139). LAMP is involved in lysosomal stability and autophagy (PMID: 12221139). This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may play a role in tumor cell metastasis (PMID 9426697). |
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