NF-H/NF200 Polyclonal antibody proteintech 18934-1-AP

$449.00
In stock
SKU
18934-1-AP

 

NEFH, Neurofilament heavy polypeptide, NF200, NF-H, 200 kDa neurofilament protein

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (2) Immunogen: CatNo: Ag13517 Product name: Recombinant human NF200 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-214 aa of BC014185 Sequence: MMSFGGADALLGAPFAPLHGGGSLHYALARKGGAGGTRSAAGSSSGFHSWTRTSVSSVSASPSRFRGAGAASSTDSLDTLSNGPEGCMVAVATSRSEKEQLQALNDRFAGYIDKVRQLEAHNRSLEGEAAALRQQQAGRSAMGELYEREVREMRGAVLRLGAARGQLRLEQEHLLEDIAHVRQRLDDEARQREEAEAAARALARFAQEAEAARV Predict reactive species
 Applications: WB, IHC, IF-P, IF-Fro, ELISA Observed Molecular Weight: 112 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC014185
Conjugate: Unconjugated Gene Symbol: NF-H
Tested Applications: Positive WB detected in Gene ID (NCBI): 4744
Application: Western Blot (WB) RRID: AB_10640801
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: NEFH (NF200), also named as KIAA0845 and NFH, belongs to the intermediate filament family. It has an important function in mature axons that is not subserved by the two smaller NF proteins. Neurofilaments are the 10 nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE: NF-L, 65-68 kDa; NF-M,145-160 kDa and NF-H, 200-220 kDa. This antibody can recognize both NEFH and NEFM.

 

 

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