Anti-Human CCL20/MIP-3 alpha Rabbit Recombinant Antibody proteintech 98221-1-RR
$299.00
In stock
SKU
98221-1-RR
CCL20, MIP-3 Alpha, MIP-3α, 241694B2, Beta-chemokine exodus-1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: chemokine (C-C motif) ligand 20 |
| Applications: FC (Intra) | Observed Molecular Weight: NM_004591.3 |
| Formulation: PBS, Azide | GenBank Accession Number: 6364 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC (Intra) detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) (INTRA) | RRID: Protein A purfication |
| Dilution: FC (INTRA) : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: P78556-1 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: CCL20, also known as macrophage in?ltrating factor protein 3α, is a C-C chemokine that speci?cally binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta. |
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