AFP Recombinant monoclonal antibody proteintech 82982-6-RR
$449.00
In stock
SKU
82982-6-RR
230435E3, Alpha fetoglobulin, alpha fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: alpha-fetoprotein |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 68 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: AFP |
| Conjugate: Unconjugated | Gene Symbol: 174 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670732 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: AFP (Alpha-fetoprotein) is a major plasma protein in the fetus and its concentration is very low in the adult (PMID:24120489). AFP can be detected at abnormally high concentrations in hepatocellular carcinomas as well as in the plasma and ascitic fluid of adults with hepatoma, indicating that AFP can serve as a tumor marker (PMID: 18669658). AFP is also a glycosylated protein and based on its binding capability to lectin Lens Culinaris Agglutinin (LCA), and total AFP can be separated into three different glycoforms, AFP-L1, AFP-L2, and AFP-L3. Core-fucosylated form of AFP (AFP-L3) is a more specific indicator than total AFP for HCC (PMID: 33128033, 35458505) |
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