AES Recombinant monoclonal antibody proteintech 83878-5-RR
$449.00
In stock
SKU
83878-5-RR
TLE5, 240987D9, AES 1, AES 2, Amino-terminal enhancer of split
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: amino-terminal enhancer of split |
| Applications: WB, ELISA | Observed Molecular Weight: 22-29 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: AES |
| Conjugate: Unconjugated | Gene Symbol: 166 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671462 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Amino-terminal enhancer of split (AES), belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members in order to forcefully repress the expression of other family member genes. AES can repress NFkB-regulated gene expression and is believed to have a significant role in initiating and maintaining cell differentiation events. AES has been found to suppress local invasion and intravasation through inhibition of the Notch pathway, leading to preventing the metastatic spread of endogenous tumors(PMID: 33754069). |