Phospho-STAT5A (Ser726)/STAT5B (Ser731) Recombinant monoclonal antibody proteintech 80138-2-RR
$449.00
In stock
SKU
80138-2-RR
p STAT5 (Ser726), p STAT5A, p STAT5A (Ser726), p STAT5A Ser726, Phospho STAT5 (Ser726)
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: Human And More (1) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 794 aa, 92 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC027036 |
| Conjugate: Unconjugated | Gene Symbol: STAT5A |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 6776 |
| Application: Western Blot (WB) | RRID: AB_3670468 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: STAT5 proteins consisting of STAT5A and STAT5B are the main targets of IL-3 signaling. Upon cytokine stimulation, JAK2 phosphorylates STAT5 and the phosphorylated STAT5 proteins dimerize and translocate into the nucleus, where, by binding DNA, they activate target genes including c-fos. In addition to this JAK-catalyzed tyrosine phosphorylation, STAT5 may undergo serine phosphorylation in the carboxy-terminal P(M)SP site in response to prolactin. (PMID: 15795318) |
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