UPF1 Recombinant monoclonal antibody proteintech 82791-1-RR
$449.00
In stock
SKU
82791-1-RR
RENT1, Regulator of nonsense transcripts 1, KIAA0221, EC:3.6.4.12, ATP-dependent helicase RENT1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, rat | Immunogen: UPF1 regulator of nonsense transcripts homolog (yeast) |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 123-130 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: UPF1 |
| Conjugate: Unconjugated | Gene Symbol: 5976 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3086538 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Liquid |
| Tested Reactivity: Human, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Up-Frameshift Suppressor 1 Homolog (UPF1) is the central factor in nonsense-mediated mRNA decay (NMD) and is also directly involved in telomere homeostasis, DNA replication, histone mRNA degradation and staufen-mediated mRNA decay (PMID: 29382845). It is a potential modulator of MALAT1 and that UPF1/MALAT1 pathway could be a therapeutic target for gastric cancer (PMID: 28942451). The molecular mass of UPF1 is 123-130 kDa. |
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